The Study of Yin-Chen-Hao-Tang Preventing and Treating Alcoholic Fatty Liver Disease through PPAR Signaling Pathway Based on Network Pharmacology and RNA-Seq Transcriptomics

Table 4

Fold change of differential expression genes downregulated by ethanol and upregulated by YCHT.

Gene name	FC (E/C)	FC (Y/E)	Gene name	FC (E/C)	FC (Y/E)
8430408G22Rik	0.32	4.49	Gm43305	0.21	2.49
Acot1	0.16	2.74	Gm4952	0.46	2.09
Amotl2	0.33	2.22	Hes1	0.49	2.32
Apc	0.45	2.31	Il1r1	0.16	3.74
Arhgef37	0.38	2.74	Kpna1	0.24	4.19
Arntl	0.32	2.25	Map3k13	0.27	2.30
Cdkn1a	0.19	2.89	Nr0b2	0.22	6.26
Chrna2	0.32	3.02	Otud1	0.33	2.11
Clec2h	0.05	11.97	Pdk4	0.07	4.34
Clpx	0.36	2.33	Pfkfb1	0.41	2.14
CYP26a1	0.42	2.15	Ppm1k	0.46	2.26
CYP4a10	0.30	3.23	Ppp1r3c	0.41	2.18
CYP4a14	0.26	2.84	Rnf186	0.33	2.55
CYP4a31	0.28	2.37	Rnf24	0.37	2.26
CYP4a32	0.48	2.37	Scara5	0.12	8.89
D630039A03Rik	0.43	2.09	Sgk2	0.35	2.35
Ehhadh	0.18	2.80	Slc25a30	0.44	2.01
Elovl3	0.19	6.93	Smad9	0.14	2.91
Fam107a	0.05	4.84	Ttll8	0.20	3.09
Fam134b	0.34	2.62	Upp2	0.18	2.18
Fkbp5	0.42	2.08	Zbtb16	0.23	3.75

Notes. C: control group; E: ethanol group; Y: YCHT group; FC: fold change.