Review Article

Comparison of Herbal Agents with Sodium Hypochlorite as Root Canal Irrigant: A Systematic Review of In Vitro Studies

Table 5

The results of the assessment.

Author and yearReduction in bacterial loadOutcome

Ok et al. 2015 [5]Mean of the Log10 CFU and SD: 1% oregano extract—1.404 ± 1.803 CFU/ml and 5.25% NaOCl—2.308 ± 1.739 CFU/ml1% oregano extract solution showed a similar result to 5.25% NaOCl
Pujar et al. 2011 [11]Mean of the Log10 CFU and SD: triphala 2.3 ± 0.59 × 104 CFU/ml, green tea 3.8 ± 0.79 × 104 CFU/ml, and 3% NaOCl 0.00Hypochlorite exhibited the maximum bacterial inhibition compared to triphala and green tea extract
Choudhary et al. 2018 [12]Mean of the Log10 CFU and SD: Morinda citrifolia 3.51 ± 0.29, triphala 3.37 ± 0.56, and 1% NaOCl 1.43 ± 0.53Compared to 1% NaOCl, morinda and triphala showed reduced effectiveness
Sedigh-Shams et al. 2015 [13]% bacterial CFU reduction: Z. multiflora (2 times of MFC)—200,000 ± 0 5% NaOCl- 200,000 ± 0 Z. multiflora MFC—199,540 ± 313Both Z. multiflora (2 times of MFC) and 5% NaOCl showed similar antimicrobial efficiency
Rosaline et al. 2013 [14]% remaining bacterial adhesion to dentin: Azadiracta indica 9.30% and 5.25%, NaOCl 12.50%, green tea 27.30%, and Morinda citrifolia 44.20%Compared to 5.25% NaOCl, Azadiracta indica showed reduced bacterial adherence
Gupta-Wadhwa et al. 2016 [15]Ocimum sanctum— 2.65 × 105, Cinnamomum zeylanicum—1.535 × 105, Syzygium aromaticum—1.425 × 105, and 3% NaOCl—1.402 × 104Compared to other herbal agents, 3% NaOCl showed better antimicrobial efficiency
Sharifian et al. 2009 [16]Substantivity was assessed over a period of 28 days. CFU reduction (%) ±SD: carvacrol 99.3 ± 1.54 5.25% and NaOCl 99.98 ± 0.045.25% NaOCl showed significantly better results than carvacrol
Divia et al. 2018 [17]CFU reduction ± SD: 5% NaOCl 0.67 ± 0.78, Morinda citrifolia 158.17 ± 19.83, triphala 15.92 ± 2.87, and green tea polyphenol 56.67 ± 7.18NaOCl showed the maximum antibacterial effect, followed by triphala, green tea polyphenol, and least was Morinda citrifolia
Kumar et al. 2018 [18]PCR mean value of antimicrobial efficiency: 3% NaOCl—34.20, neem—33.93, and tulsi—31.86NaOCl showed the maximum antibacterial activity, followed by neem leaf extract. The least effect was seen with tulsi