To Predict Anti-Inflammatory and Immunomodulatory Targets of Guizhi Decoction in Treating Asthma Based on Network Pharmacology, Molecular Docking, and Experimental Validation

Figure 10

Analyses of representative target protein–ingredient docking simulation. (a) Quercetin acts on IKBKB. (b) Glabrene acts on HRAS. (c) Phaseolinisoflavan acts on CHUK. (d) Glabrene acts on MAPK1. (e) Phaseolinisoflavan acts on MAPK3. (f) Ursolic acid acts on NFKB1. (g) Glabrene acts on PIK3CG. (h) Phaseolinisoflavan acts on RAF1. (i) Ursolic acid acts on RELA. The red box on the left indicated the macromolecule binding pocket. The green in the middle picture represented the ligand, and the red represented the amino acid residues connected with hydrogen bonds. The blue box on the right indicated the binding bond of docking, and the cyan rod shape represented the hydrogen bond.

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