Botanical, Traditional Use, Phytochemical, and Toxicological of Arisaematis rhizoma

Table 11

Toxicity study of Arisaematis and Arisaematis Rhizoma Preparatum.

Extract/compound	Animal	LD50/toxic dose range	Toxic effects	In vitro/in vivo	Ref.
A. amurense maxim.	Mice	0.4 mL/10g	Death	In vivo	[87]
AR	Mice	12 g/kg	60% death	In vivo	[88]
Processed AR	Mice	12 g/kg	Normal	In vivo	[88]
AR	Mice	LD50 = 155.78 g/kg^−1	Death	In vivo	[89]
AR	Mice	LD50 = 21.508 g/kg^−1	Death	In vivo	[90]
AR needle crystal	Mice	LD50 = 42.53 mg·kg^−1	Death	In vivo	[91]
AR powder	Mice	LD50 = 1,062 mg·kg^−1	The abdomen is swollen, and the fur is dull	In vivo	[91]
Processed AR powder	Mice	LD50 = 2,788 mg·kg^−1	The abdomen is swollen, and the fur is dull	In vivo	[91]