Microencapsulated Recombinant Human Epidermal Growth Factor Ameliorates Osteoarthritis in a Murine Model

Figure 5

Inflammatory cytokines in circulating serum. The levels of (a) IL-1β, IL-6, TNF-α, and IL-17A and (b) inflammatory mediators, prostaglandin E2 (PGE2), and nitric oxide (NO) in serum samples were measured by ELISA or Griess reaction (NO) with or without treatments of HA, rhEGF, or HA/Me-rhEGF. Data are expressed as mean ± SEM from the three independent experiments.

(a)

(b)