GuanXinNing Tablet Attenuates Alzheimer’s Disease via Improving Gut Microbiota, Host Metabolites, and Neuronal Apoptosis in Rabbits

<div>GXN improved colon barrier permeability and the diversity of gut microbiota in AD rabbits. (a) Typical images of AB-PAS staining in the colon tissue. Scale bar = 500 mm. Black boxes indicate the areas shown at higher magnification. (b) Quantitative analysis of the number of AB-PAS-positive cells per crypt in each group. Chao1 (c) and Shannon (d) indices of <i>α</i>-diversity were assessed. (e) Principal coordinate analysis (PCoA) of the <i>β</i>-diversity index. <i>n</i> = 5.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 5

Figure 5: GuanXinNing Tablet Attenuates Alzheimer’s Disease via Improving Gut Microbiota, Host Metabolites, and Neuronal Apoptosis in Rabbits 