Research Article
Role of Episamarcandin in Promoting the Apoptosis of Human Colon Cancer HCT116 Cells through the PI3K-Akt Signaling Pathway
Table 1
Cytotoxicity of compounds against HCT116 and SGC-7901 cell lines.
| | Compounds | HCT116 IC50 (μg·mL−1) | SGC-7901 IC50 (μg mL−1) | | MTT assay | SRB assay | MTT assay | SRB assay |
| | Fekolone | >50 | >50 | >50 | >50 | | Sinkianone | >50 | >50 | >50 | >50 | | Lehmannolone | >50 | >50 | >50 | >50 | | Fekrynol | 31.56 ± 2.68 | 35.84 ± 2.79 | 40.41 ± 3.12 | 45.24 ± 3.76 | | Colladonin | >50 | >50 | >50 | >50 | | Feselol | >50 | >50 | >50 | >50 | | Compound 7 | >50 | >50 | >50 | >50 | | Lehmannolol | >50 | >50 | >50 | >50 | | Episamarcandin | 26.06 ± 1.28 | 29.71 ± 2.12 | 30.14 ± 2.76 | 34.97 ± 3.12 | | Isosamarcandin | >50 | >50 | >50 | >50 | | Sinkiangenorin E | >50 | >50 | >50 | >50 | | Compound 12 | 40.24 ± 3.94 | 42.78 ± 4.12 | >50 | >50 | | Sinkiangenorin F | >50 | >50 | >50 | >50 |
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