Deciphering Pharmacological Mechanism of Buyang Huanwu Decoction for Spinal Cord Injury by Network Pharmacology Approach

Table 3

The enriched 15 possible related pathways for SCI.

ID	Description	P value	Adjusted P value	Gene number
hsa04933	AGE-RAGE signaling pathway in diabetic complications	8.58479E−34	2.24063E−31	35
hsa04668	TNF signaling pathway	8.83261E−24	3.84219E−22	29
hsa04210	Apoptosis	1.13129E−15	1.42828E−14	24
hsa05022	Pathways of neurodegeneration - multiple diseases	1.12387E−14	1.0476E−13	41
hsa04620	Toll-like receptor signaling pathway	5.71758E−14	4.52208E−13	20
hsa04151	PI3K-Akt signaling pathway	1.43931E−13	1.00595E−12	34
hsa04066	HIF-1 signaling pathway	1.4646E−13	1.00595E−12	20
hsa04010	MAPK signaling pathway	5.84978E−12	3.39287E−11	29
hsa04064	NF-kappa B signaling pathway	7.32616E−12	4.1568E−11	18
hsa01521	EGFR tyrosine kinase inhibitor resistance	1.25843E−09	5.13202E−09	14
hsa04012	ErbB signaling pathway	3.21508E−08	1.0622E−07	13
hsa04630	JAK-STAT signaling pathway	4.40433E−07	1.27726E−06	16
hsa04310	Wnt signaling pathway	0.000748937	0.001515292	11
hsa04152	AMPK signaling pathway	0.001230137	0.002407294	9
hsa04150	mTOR signaling pathway	0.002091493	0.003927191	10