Effect of Gegen Qinlian Decoction on Hepatic Gluconeogenesis in ZDF Rats with Type 2 Diabetes Mellitus Based on the Farnesol X Receptor/Ceramide Signaling Pathway Regulating Mitochondrial Metabolism and Endoplasmic Reticulum Stress

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left">Gene</td><td class="align_center">F (5′⟶3′)</td><td class="align_center">R (5′⟶3′)</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">FXR</td><td class="align_center">GGACACGCAGACCTGTTGGA</td><td class="align_center">GGATGACAATTGCTGTGAGCAGA</td></tr><tr><td class="align_left">Sptlc2</td><td class="align_center">CAGACTGTCGGGAGCAACCA</td><td class="align_center">CTTGTCCGAGGCTGACCATAAAC</td></tr><tr><td class="align_left">Smpd3</td><td class="align_center">CTGTGGACTCAGGGCTCGTGTA</td><td class="align_center">GCCTTGTCACGGAATCTGGAA</td></tr><tr><td class="align_left">PERK</td><td class="align_center">TTCAATGCGTGGCTGGAAAC</td><td class="align_center">AGGATCCATCTGCCGGATCTTA</td></tr><tr><td class="align_left">ATF6α</td><td class="align_center">GAGGCTCAAAGTCCCAAGTCCA</td><td class="align_center">GGCAGGGCTCACACTAGGTTTC</td></tr><tr><td class="align_left">GRP78 BiP</td><td class="align_center">TCAGCCCACCGTAACAATCAAG</td><td class="align_center">TCCAGTCAGATCAAATGTACCCAGA</td></tr><tr><td class="align_left">IRE1</td><td class="align_center">CATCACCATGTATGACACCAAGACC</td><td class="align_center">TGTCCACAGTTACCACCAGTCCA</td></tr><tr><td class="align_left">CS</td><td class="align_center">TGGCCCAACGTAGATGCTCA</td><td class="align_center">AGCCTAGGGCTCTGCTCCAGATA</td></tr><tr><td class="align_left">PC</td><td class="align_center">CCTACAGCTGCCACCAAGATGA</td><td class="align_center">CCACAATGCCCGCTAGGAAC</td></tr><tr><td class="align_left">β-Actin</td><td class="align_center">GGAGATTACTGCCCTGGCTCCTA</td><td class="align_center">GACTCATCGTACTCCTGCTTGCTG</td></tr><tr><td class="align_left">COX4</td><td class="align_center">TGTTGGCTACCAGGGCACTTA</td><td class="align_center">GGTAGTCACGCCGATCAACATA</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Evidence-Based Complementary and Alternative Medicine

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Table 1

Table 1: Effect of Gegen Qinlian Decoction on Hepatic Gluconeogenesis in ZDF Rats with Type 2 Diabetes Mellitus Based on the Farnesol X Receptor/Ceramide Signaling Pathway Regulating Mitochondrial Metabolism and Endoplasmic Reticulum Stress

Table 1 | Effect of Gegen Qinlian Decoction on Hepatic Gluconeogenesis in ZDF Rats with Type 2 Diabetes Mellitus Based on the Farnesol X Receptor/Ceramide Signaling Pathway Regulating Mitochondrial Metabolism and Endoplasmic Reticulum Stress 