Research Article

Molecular Targets and Mechanisms of Scutellariae radix-Coptidis rhizoma Drug Pair for the Treatment of Ulcerative Colitis Based on Network Pharmacology and Molecular Docking

Table 3

Core targets of active ingredients in the Scutellariae radix-Coptidis rhizoma drug pair.

RankNameDegree ≥ 10Closeness centralityNeighbourhood connectivity

1PTGS2370.524822.3429
2PTGS1330.516622.9375
3HSP90AB1300.500923.4667
4PRKACA260.500924.5200
5AR250.451425.5652
6SCN5A240.477526.5652
7NCOA2240.480924.7391
8PRSS1230.448427.5238
9NOS2230.322819.6190
10CALM1220.352921.5909
11DPP4170.436829.4706
12RXRA160.453031.4667
13ADRB2150.462532.8000
14KCNH2150.436630.9231
15PIK3CG140.451532.4286
16NOS3140.397329.8182
17ESR1130.307818.1818
18F10110.421332.2727
19NCOA1100.323624.0000