Activity Screening of the Herb Caesalpinia sappan and an Analysis of Its Antitumor Effects

Table 2

The inhibitory effect of SY② and SG② (n = 3, mean ± SD).

Group	Dose (μg/ml)	First experiment			Second experiment
		OD value	IR1 (%)	IC50 (μg/ml)	OD value	IR1 (%)	IC50 (μg/ml)
PBS	—	0.1838 ± 0.0082	0	—	0.1860 ± 0.0068	0	—
DMSO	—	0.1752 ± 0.0028	0	—	0.1790 ± 0.0104	0	—
SY②	200	0.0500 ± 0.0164	71.5	76.6	0.0523 ± 0,0169	71.6	77.8
	100	0.0843 ± 0.0460	51.9		0.0912 ± 0.0470	50.5
	50	0.0990 ± 0.0380	43.5		0.1007 ± 0.0437	43.6
	25	0.1247 ± 0.0190	28.9		0.1300 ± 0.0251	29.5
	12.5	0.1510 ± 0.0318	13.9		0.1607 ± 0.0267	12.8
SG②	200	0.0390 ± 0.0204	77.7	56.05	0.0413 ± 0.0212	76.9	56.14
	100	0.0733 ± 0.0458	58.2		0.0700 ± 0.0396	60.9
	50	0.0841 ± 0.0338	52.0		0.0877 ± 0.0360	51.0
	25	0.1027 ± 0.0317	41.4		0.1053 ± 0.0291	41.2
	12.5	0.1520 ± 0.0211	13.2		0.1560 ± 0.0250	12.8
Epirubicin	20	0.0289 ± 0.0112	83.5	5.42	0.0273 ± 0.0103	84.7	4.79
	10	0.0667 ± 0.0103	61.9		0.0657 ± 0.0104	63.3
	5	0.0898 ± 0.0189	48.7		0.0839 ± 0.0183	53.1
	2.5	0.1135 ± 0.0121	35.2		0.1102 ± 0.0118	38.5
	1.25	0.1563 ± 0.0134	10.7		0.1545 ± 0.0133	13.6