Activity Screening of the Herb Caesalpinia sappan and an Analysis of Its Antitumor Effects

Table 5

Pathological changes in tumor tissue and the expression of VEGF and PCNA factors (n = 10, mean ± SD).

Group	Dose (mg/kg)	Scores^a	VEGF^b	PCNA^c
Control group	—	4.31 ± 0.54	174.915 ± 1.7091	63.13 ± 3.78
FU group	83	6.57 ± 0.43	141.21 ± 0.9003	46.12 ± 4.45
i.p. group	65	5.20 ± 0.46	144.189 ± 1.0205	52.80 ± 3.90
	20	4.30 ± 0.42	131.066 ± 0.9191	57.40 ± 2.82
i.g. group	325	4.50 ± 0.17	132.924 ± 1.7579	48.70 ± 2.62
	100	5.60 ± 0.43	139.358 ± 1.3292	41.10 ± 4.62

^aTumor cell lesion score (HE staining). ^bVEGF-positive tumor cells. ^cPCNA-positive tumor cells. Compared with the control group, and .