The Synergistic Beneficial Effect of Thyme Honey and Olive Oil against Diabetes and Its Complications Induced by Alloxan in Wistar Rats

Table 8

Effect of daily administration of thyme honey, olive oil, and their combination on liver enzymatic antioxidants of diabetic and nondiabetic rats.

Variables in the liver	Interventions
	DW	OO	TH	DC	DC + OO	DC + TH	DC + OO + TH
Proteins (mg/g org)	7.71 ± 0.57	7.70 ± 0.56	7.72 ± 0.56	5.31 ± 0.28	5.33 ± 0.19	7.16 ± 0.11	6.99 ± 0.18
Catalase (μmol H2O2/min/mg pr)	31.84 ± 0.8	31.83 ± 1.03	31.85 ± 0.91	11.04 ± 1.67	29.66 ± 0.31	30.00 ± 1.60	30.98 ± 2.15
GSH (μg/g org)	412.44 ± 4.94	412.33 ± 4.99	411.98 ± 5.18	236.47 ± 6.01	408.44 ± 5.33	410.44 ± 5.28	409.73 ± 6.94
GPx (nmol GSH/min/mg pr)	14.47 ± 0.31	14.48 ± 0.28	14.50 ± 0.21	9.93 ± 0.63	10.83 ± 0.87	9.88 ± 0.54	11.69 ± 1.11
MDA (nmol/g org)	38.81 ± 0.55	38.18 ± 0.60	37.28 ± 0.80	77.88 ± 2.03	41.40 ± 1.52	39.75 ± 0.50	40.63 ± 1.52

Data presented as mean ± SD; a: comparison between distilled water group (DW) and all groups; b: comparison between diabetic nontreated group (DC) and all groups; c: comparison between the diabetic group treated by olive oil (DC + OO) and the diabetic group treated by thyme honey (DC + TH); d: comparison between the diabetic group treated by the combination between olive oil and thyme honey (DC + OO + TH) and the groups treated by olive oil only (DC + OO) or thyme honey only (DC + TH).