Evidence-Based Complementary and Alternative Medicine

Review Article

Systematic Review with Meta-Analysis: Effectiveness and Safety of Acupuncture as Adjuvant Therapy for Side Effects Management in Drug Therapy-Receiving Breast Cancer Patients

Table 2

Assessment of certainty of evidence using the GRADE approach.
Certainty assessmentCertainty
Name of studyRisk of biasIndirectnessInconsistencyImprecisionPublication bias
Bao et al. 2013 [16]Not seriousNot seriousSeriousSeriousLow probability⊕⊕○○Low
Crew et al. 2010 [15]Not seriousNot seriousSeriousNot seriousHigh probability⊕⊕○○Low
Greenlee et al. 2016 [18]SeriousNot seriousNot seriousNot seriousLow probability⊕⊕⊕○Moderate
He 2017 [13]SeriousNot seriousNot seriousNot seriousLow probability⊕⊕⊕○Moderate
Hershman et al. 2018 [21]Not seriousNot seriousNot seriousNot seriousLow probability⊕⊕⊕⊕High
Li 2017 [20]SeriousNot seriousNot seriousNot seriousLow probability⊕⊕⊕○Moderate
Liu 2014 [17]SeriousNot seriousNot seriousNot seriousHigh probability⊕⊕○○Low
Lu et al. 2020 [26]SeriousNot seriousNot seriousNot seriousLow probability⊕⊕⊕○Moderate
Mao et al. 2014 [12]Not seriousNot seriousNot seriousNot seriousLow probability⊕⊕⊕⊕High
Quinlan-Woodward et al. 2016 [19]SeriousNot seriousNot seriousNot seriousLow probability⊕⊕⊕○Moderate
Shen et al. 2000 [14]Not seriousNot seriousNot seriousNot seriousHigh probability⊕⊕⊕○Moderate
Shi 2019 [24]Not seriousNot seriousSeriousSeriousHigh probability⊕○○○Very low
Tong et al. 2018 [22]SeriousNot seriousNot seriousNot seriousLow probability⊕⊕⊕○Moderate
Zhang 2018 [23]Not seriousNot seriousSeriousNot seriousHigh probability⊕⊕○○Low
Zhang 2019 [25]Not seriousNot seriousSeriousNot seriousHigh probability⊕⊕○○Low
Zhang et al. 2020 [27]Not seriousNot seriousNot seriousNot seriousLow probability⊕⊕⊕⊕High