Review Article

Review of Traditional Chinese Medicines for Common Complications Related to Hemodialysis: An Evidence-Based Perspective

Table 1

Description of traditional herbal medicine viewpoints and treatments for acute hemodialysis-related complications in this review.

ComplicationTCM diseaseSymptom and signEtiology and pathogenesisMethodTreatmentReference

Intradialytic hypotensionDizziness syndrome/juc collapse/asthenic diseaseCold clammy limbs, general weakness, shortness of breath, and sweatingDeficiency syndromeYang-Qi deficiency of spleen and kidneyNANA[17]
Excess syndromeBlood stasis, dampness, windiness, and water vapor
Early stageDeficiency of both Qi and YinCHMSheng Mai Yin, Rx. Astragali[18]
Late stageQi desertion along with fluid and blood depletionShen Fu decoction
Deficiency of kidney-YangHATSemen Sinapis, Rhizoma Corydalis, and Hb. cum Rx. Asari applied to Yongquan (KI1) and Guanyuan (RN4)[19]
Deficiency in origin and excess in superficialityDampness and heat with deficiency of both Qi and YinCHMSheng Mai Yin and Si Miao San decoction[27]

Intradialytic hypertensionDizziness syndromeHeadaches, fatigue or confusion, vision problems, chest painHyperactivity of liver-YangAcuSanyinjiao (SP6), Taixi (KI3), and Shenguan (LE44)[32]
Deficiency of kidney-YinEAErbeixin (P1), Erjian (EX-HN6), liver (CO12), Jiaowoshang (TF1)[33]
Deficiency of Yin and YangSpleen (CO13), kidney (CO10), Erbeipi (P3), Erbeigou (PS)
Interior retention of phlegm and dampnessSanjiao (CO17), spleen (CO13), Erbeipi (P3), Erbeigou (PS), Jiaogan (AH6a)
Deficiency of Yang floating upwardHATRz. Chuanxiong, Rx. Achyranthis Bidentatae, Fr. Evodiae applied to Yongquan (KI1)

Muscle crampsJin Bi/Bi-syndromeTonic contraction and myalgiaStagnation of coldness in the musclesMoxZusanli (ST36), Sanyinjiao (SP6), and Guanyuan (CV4)[38]
Malnutrition of liver, spleen, and kidneyAcupressureHegu (LI4), Taichong (LR3), Chengshan (BL57), Chengjin (BL56), Yanglingquan (GB34), and Zusanli (ST36)[39]
Chengshan (BL57), Shuigou (GV26), Taichong (LR3), Guanyuan (CV4), Qihai (CV6), Yongquan (KI1), Lieque (LU7), and Taiyuan (LU9)[40]
Deficiency of liver and kidneyAcuQuquan (LR8), Fuliu (KI7), Guanyuan (CV4), Qimen (LR14), Ganshu (BL18), and Shenshu (Bl23)[41]
Deficiency of Yin and blood, malnutrition of the tendons and channelsCHMShao Yao Gan Cao Tang[43, 44]

Nausea and vomitingRetching/hiccup/vomitingNausea, vomiting, anorexia, allotriogeusia, headacheDeficiency of spleen and kidneyHATZingiber officinale applied on Shenque (CV8)[47]
AcuZhongwan (CV12), Neiguan (PC6), and Zusanli (ST36)
Cold blocking the channels due to blood deficiency, incoordination between the spleen and liver resulting in rebellious QiCHMDang Gui Si Ni Tang plus Fr. Evodiae and Rz. Zingiberis Recens[50]

HeadacheTrue headacheā€‰Liver dysfunction in dispersion, deficiency of Qi, blood and Yin essence, and stasis of bloodEAShenmen (TF4), subcortex (AT4), occiput (AT3), kidney (CO10), liver (CO12), and spleen (CO13)[53]

Chest painChest impedimentPressure, fullness, burning, or tightness in chestDeficiency in origin and excess in superficialityDeficiency of kidney-Qi and insufficiency of heart-blood, resulting in phlegm-dampness, or stasis blocking heart collateralsCHMShe Xiang Bao Xin Pill[56]

Dialysis disequilibrium syndromeHeadache/dizziness syndrome/vomiting/convulsion diseasesNausea, headache, vomiting, restlessness, and even seizures and comaDeficiency of spleen and kidney, insufficient gasification causes phlegm turbidity retentionCHMWu Ling San[64]
CHMWen Yang Li Shui Tang[65]
AcuTaichong (LR3), Fengchi (GB20), Baihui (GV20), Sishencong (EXHN 1), Xingjian (LR2), Neiting (ST44), and Xiaxi (GB43)[69]

Acu: acupuncture; CHM: Chinese herbal medicine; EA: ear acupuncture; HAT: herbal acupoint therapy; Mox: moxibustion; NA: not applicable.