The Anti-Inflammatory Effect of Smilax china L. Extract on LPS-Stimulated THP-1 via Downregulation of MAPK and NF-κB Signaling Pathway

Figure 3

In vivo anti-inflammatory activity of ES. ES and JGT capsule inhibited xylene-induced ear oedema in mice (a) and egg white-induced plantar swelling in rats (b). Saline (model group), ES (the extract at the doses equalling to 13.5 and 27 g/kg in mice, 10 and 20 g/kg in rats), and JGT (the extract at the dose equalling to 13.5 g/kg in mice, 10 g/kg in rats) were orally administered, respectively. The mouse ear oedema and rat plantar swelling were induced, and the inhibitory activities were calculated as described in Materials and Methods, respectively. Data are presented as means ± SD (n = 10). and versus the model group.

(a)

(b)