Research Article

Aqueous Extract of Dacryodes edulis (Burseraceae) Leaves Inhibited Tumor Growth in Female Wistar Rats with 7,12-Dimethylbenz[a]anthracene-Induced Breast Cancer

Table 2

Percentage inhibition of tumor growth following treatments.

Tumor volume in cm3 (percentage inhibition of tumor growth)
Week 0Week 1Week 2Week 3

DMBA + DW0.72 ± 0.162.61 ± 0.583.49 ± 0.783.98 ± 0.79
DMBA + TAM0.47 ± 0.121.04 ± 0.23 (60%)1.75 ± 0.39 (50%)2.40 ± 0.34(38%)
DMBA + AE 250.46 ± 0.12.11 ± 0.47 (19%)2.63 ± 0.58 (25%)3.56 ± 0.71 (11%)
DMBA + AE 1000.39 ± 0.11.75 ± 0.39 (33%)2.04 ± 0.54 (42%)3.15 ± 0.63 (21%)

DMBA: 7,12-dimethylbenz[a]anthracene; DW: distilled water; TAM: tamoxifen; AE: aqueous extract of D. edulis leaves. Data are expressed as mean ± SEM (n = 5); , , and as compared to DMBA + DW.