Aqueous Extract of Dacryodes edulis (Burseraceae) Leaves Inhibited Tumor Growth in Female Wistar Rats with 7,12-Dimethylbenz[a]anthracene-Induced Breast Cancer

Table 3

Effects of treatment on oxidative stress-related parameters in breast tumors.

Groups	MDA (μM/1000 mg of tissue)	Catalase (μmol/mg of total proteins)	SOD Unit of SOD/ml/mg of tissue	Total proteins (mg/dl)
DMBA + DW	1.21 ± 0.27	0.36 ± 0.1	2.88 ± 0.64	1.49 ± 0.33
DMBA + TAM	1.63 ± 0.36	0.94 ± 0.21^###	4.27 ± 0.95^###	1.07 ± 0.24^###
DMBA + AE 25	1.77 ± 0.41	0.7 ± 0.15^##	3.44 ± 0.77	1.64 ± 0.36
DMBA + AE 100	1.84 ± 0.39^#	0.84 ± 0.19^###	3.89 ± 0.87^##	1.42 ± 0.31

DMBA: 7,12-dimethylbenz[a]anthracene; DW: distilled water; TAM: tamoxifen; AE: aqueous extract of D. edulis leaves. Data are expressed as mean ± SEM (n = 5). Histomorphology of breast tumors.