Acute and Subchronic Toxicological Evaluation of the Herbal Product HAD-B1 in Rats

Table 4

Relative organ weights (organ weight/body weight, %) of rats for 4-week recovery period.

Group		Liver		Kidney		Heart	Brain	Spleen	Testis		Epididymis		PG	SG	Lung	Thymus	Adrenal gland		Pituitary gland
				L	R				L	R	L	R					L	R
Male	G1 (0)	Mean	2.36	0.35	0.34	0.32	0.43	0.18	0.34	0.34	0.18	0.18	0.15	0.16	0.38	0.09	0.006	0.005	0.003
		SD	0.22	0.02	0.03	0.01	0.03	0.02	0.02	0.02	0.02	0.01	0.02	0.02	0.03	0.01	0.001	0.001	0.001
	G4 (2000)	Mean	2.51	0.33	0.36	0.30	0.40	0.14	0.31	0.31	0.16	0.16	0.14	0.15	0.36	0.08	0.007	0.006	0.003
		SD	0.18	0.004	0.004	0.01	0.04	0.01	0.04	0.05	0.02	0.02	0.04	0.01	0.05	0.01	0.002	0.002	0.001
Group		Liver		Kidney		Heart	Brain	Spleen	S.G	Lung	Thymus	Uterus			Adrenal gland		Ovary		Pituitary gland
				L	R										L	R	L	R
Female	G1 (0)	Mean	2.50	0.34	0.36	0.33	0.69	0.17	0.18	0.48	0.11	0.22			0.014	0.013	0.016	0.018	0.008
		SD	0.17	0.02	0.03	0.03	0.08	0.02	0.02	0.03	0.01∗	0.04			0.002	0.002	0.002	0.002	0.002
	G4 (2000)	Mean	2.59	0.32	0.34	0.36	0.69	0.18	0.18	0.48	0.08	0.29			0.013	0.013	0.015	0.016	0.007
		SD	0.09	0.04	0.04	0.03	0.05	0.02	0.02	0.02	0.01	0.08			0.002	0.001	0.002	0.003	0.002

Number of animals: 5; SD: standard deviation; PG: prostate gland; SG: salivary gland; unit: %. Significant difference as compared with control, . Number of animals: 5; SD: standard deviation; SC: salivary gland; unit: %. Significant difference as compared with control, .