Research Article
Acute and Subchronic Toxicological Evaluation of the Herbal Product HAD-B1 in Rats
Table 8
Histopathological findings of rats for 4-week recovery.
| Organ | N | Histological findings | Male | Female | G1 | G4 | G1 | G4 |
| Liver | 5 | Inflammatory cell foci | Minimal, multifocal | 0 | 0 | 1 | 0 | Kidney | 5 | Tubular basophilia | Minimal, multifocal | 1 | 1 | 0 | 0 | Medullary cyst | Present | 0 | 1 | 0 | 0 | Adrenal gland | 5 | Cortical vacuolation | Slight, diffuse | 0 | 1 | 0 | 0 | Heart | 5 | Inflammatory cell infiltration | Minimal, multifocal | 1 | 0 | 0 | 0 | Lung | 5 | Alveolar macrophage infiltration | Minimal, multifocal | 1 | 0 | 0 | 0 |
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