Research Article
Leishmanicidal Activity and Ultrastructural Changes of Maslinic Acid Isolated from Hyptidendron canum
Figure 4
Ultrastructural changes induced by maslinic acid a b, and c, miltefosine d, or amphotericin B e in promastigote forms of L. (L.) infantum. Promastigote forms were incubated with EC50 of maslinic acid A, B, and C, miltefosine D, or amphotericin B E for 24h; then morphological changes were recorded. Control parasites are shown in F. N, nucleus; FP, flagellar pocket; K, kinetoplast. Black arrow indicates blebs in the cell membrane. Black arrow head indicates compartmentalized membrane debris.
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