Anticholinesterase Activity of Eight Medicinal Plant Species: In Vitro and In Silico Studies in the Search for Therapeutic Agents against Alzheimer’s Disease

Figure 2

The selected compounds isolated from leaves of Blumea lacera for molecular docking with AChE and BChE. (a) 5,4′-dihydroxy 6,7,3′-trimethoxyflavone (BL1), (b) 3,5,4′-trihydroxy 6,7,3′-trimethoxyflavone (BL2), (c) 5,3′,4′-trihydroxy 3,6,7-trimethoxyflavone (BL3), (d) 5-hydroxy 3,6,7,3′,4′-pentamethoxyflavone (BL4), (e) Kaempferol-3-O-α-L-rhamnopyranosyl-(1⟶6)-β-D-glucopyranoside (BL5), (f) Kaempferol-3-O-(2″,6″-di-O-α-L-rhamnopyranosyl)-β-D-glucopyranoside (BL6), (g) Campesterol (BL7), (h) 19α-hydroxyurs-12-ene-24,28-dioate 3-O-β-D- xylopyranoside (BL8), (i) 25R)-3β-{O-β-D-glucopyranosyl-(1⟶ 4)-O-α-L-rhamnopyranosyl-(1⟶ 4)-[O-α-L-rhamnopyranosyl-(1⟶ 2)]-α-L-rhamnopyranosyl}-22αN-spirosol-5-ene (BL9).