Involvement of Anti-Inflammatory and Stress Oxidative Markers in the Antidepressant-like Activity of <i>Aloysia citriodora</i> and Verbascoside on Mice with Bacterial Lipopolysaccharide- (LPS-) Induced Depression

<div>The timeline of the experimental design of the pretreatment (a) and posttreatment (b) stages in the evaluation of the antidepressant-like activity of the hydroalcoholic extract of <i>A citriodora</i> (HEAc) and verbascoside. Note: lipopolysaccharide (LPS; 600 <i>μ</i>g/kg, i.p). N (naive); Veh (vehicle, water); HEAc (<i>Aloysia citriodora</i> hydroalcoholic extract: 3, 30, or 300 mg/kg); VBS (verbascoside, 30 mg/kg); Flu (fluoxetine 30 mg/kg). OFT: open-field test; TST: tail suspension test.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 1

Figure 1: Involvement of Anti-Inflammatory and Stress Oxidative Markers in the Antidepressant-like Activity of <i>Aloysia citriodora</i> and Verbascoside on Mice with Bacterial Lipopolysaccharide- (LPS-) Induced Depression 

Figure 1 | Involvement of Anti-Inflammatory and Stress Oxidative Markers in the Antidepressant-like Activity of Aloysia citriodora and Verbascoside on Mice with Bacterial Lipopolysaccharide- (LPS-) Induced Depression 