Involvement of Anti-Inflammatory and Stress Oxidative Markers in the Antidepressant-like Activity of Aloysia citriodora and Verbascoside on Mice with Bacterial Lipopolysaccharide- (LPS-) Induced Depression

Table 1

Effect of HEAc and VBS on the levels of GSH and SOD activity in the hippocampus of mice evaluated in the posttreatment experiment of antidepressant-like activity.

Treatments	GSH	SOD
N	24.18 ± 3.28	22.24 ± 2.08
Veh	11.52 ± 1.29	18.10 ± 1.57
Flu	13.98 ± 0.64	25.30 ± 1.25
HEAc 30	21.34 ± 3.21^#	20.09 ± 1.63
HEAc 300	36.06 ± 1.35^###	19.32 ± 1.93
VBS	13.12 ± 1.00	20.24 ± 1.45

Note. N, naive; Veh, (vehicle, water); Flu, fluoxetine (30 mg/kg) hydroalcoholic extract of Aloysia citriodora (HEAc, 30 or 300 mg/kg); VBS, verbascoside (30 mg/kg). ANOVA (one way) (n = 8), post hoc Tuckey. and compared to the N group. ^# and ^### compared to the Veh group. Reduced glutathione (GSH; μg/mg tissue); SOD (superoxide dismutase, U/mg protein).