<i>Cordyceps militaris</i> Carotenoids Protect Human Retinal Endothelial Cells against the Oxidative Injury and Apoptosis Resulting from H<sub>2</sub>O<sub>2</sub>

<div>The impact of CMCT treatment on the expression of proteins associated with ARPE-19 cell apoptosis after H<sub>2</sub>O<sub>2</sub> exposure. (a) The cells received a 12 h CMCT pretreatment at different concentrations (0–10 <i>μ</i>g/ml), and H<sub>2</sub>O<sub>2</sub> (400 <i>μ</i>M) treatment for 12 h to examine the changes in the intracellular ROS levels. (b) Flow cytometry was used to analyze the expression of NOX1 proteins in the ARPE-19 cells following exposure to H<sub>2</sub>O<sub>2</sub> and CMCT (2.5 <i>μ</i>g/ml, 1 <i>μ</i>g/ml). The data are shown as mean ± SD for three separate replicates. 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-12Z"></path></g><g transform="matrix(.013,0,0,-0.013,43.785,0)"><path d="M241 635C89 635 35 457 35 312C35 153 89 -12 240 -12C390 -12 443 166 443 312C443 466 390 635 241 635ZM238 602C329 602 354 454 354 312C354 172 330 22 240 22C152 22 124 173 124 313S148 602 238 602Z"></path></g><g transform="matrix(.013,0,0,-0.013,50.025,0)"><path d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 27V0H384Z"></path></g></svg>.</span> Compared to the H<sub>2</sub>O<sub>2</sub> control samples: <sup>#</sup><svg height="9.2729pt" id="M28" style="vertical-align:-0.6370001pt" version="1.1" viewbox="-0.0498162 -8.6359 44.8393 9.2729" width="44.8393pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M600 480C600 590 528 650 384 650H143L137 622C222 614 225 607 210 531L130 127C113 41 106 36 23 28L17 0H294L300 28C204 36 195 42 212 127L243 284L314 263C327 263 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transform="matrix(.013,0,0,-0.013,38.365,0)"><path d="M153 550H386L412 615L406 623H120L82 318C104 327 142 338 184 338C294 338 347 275 347 187C347 112 305 39 221 39C160 39 119 71 97 89C88 97 80 96 71 90C59 80 50 67 49 57C48 45 52 36 66 23C80 9 123 -12 169 -12C221 -11 288 15 342 59C403 109 431 165 431 225C431 308 366 395 238 395C212 395 165 379 127 364L153 550Z"></path></g></svg> and <sup>##</sup><span class="nowrap"><svg height="9.2729pt" id="M29" style="vertical-align:-0.6370001pt" version="1.1" viewbox="-0.0498162 -8.6359 44.8393 9.2729" width="44.8393pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M600 480C600 590 528 650 384 650H143L137 622C222 614 225 607 210 531L130 127C113 41 106 36 23 28L17 0H294L300 28C204 36 195 42 212 127L243 284L314 263C327 263 339 263 352 264C465 271 600 337 600 480ZM508 481C508 351 402 304 329 304C289 304 265 311 250 317L295 559C302 594 310 606 323 611C335 616 350 619 367 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499V114C205 42 199 34 109 27V0H384Z"></path></g></svg>.</span></div>

Evidence-Based Complementary and Alternative Medicine

fig7

Figure 7

Figure 7: <i>Cordyceps militaris</i> Carotenoids Protect Human Retinal Endothelial Cells against the Oxidative Injury and Apoptosis Resulting from H<sub>2</sub>O<sub>2</sub> 

Evidence-Based Complementary and Alternative Medicine

Cordyceps militaris Carotenoids Protect Human Retinal Endothelial Cells against the Oxidative Injury and Apoptosis Resulting from H2O2

Figure 7

Cordyceps militaris Carotenoids Protect Human Retinal Endothelial Cells against the Oxidative Injury and Apoptosis Resulting from H₂O₂