Seungmagalgeun-Tang, a Traditional Herbal Formula, Alleviates Skin Inflammation and Depression-Like Behavior in Atopic Dermatitis Mice under Sleep Deprivation Conditions

Table 3

The docking analysis of SMGGT compounds with 13 AD-related targets.

Target		Docking score (kcal/mol)
Gene	Protein (PDB ID)	Puerarin	Paeoniflorin	Liquiritigenin	Daidzin	Ferulic acid
AKT1	AKT1 (3096)	−7.9
IFNA1	IFN-α (3UX9)	−8.9
IFNB	IFN-β (1AU1)	−7.7
IL6	IL-6 (4O9H)		−7.2
JAK3	JAK3 (5TTS)	−7.7
JUN	JUN (1JUN)	−5.8
MMP9	MMP-9 (6ESM)	−7.5
NFKBLA	IκB-α (6Y1J)	−7.9
PTGS2	COX-2 (3MQE)	−7.2		−7.3	−7.6	−5.4
STAT3	STAT3 (6NJS)	−7.9
TNF	TNF-α (2AZ5)	−8.8	−8.1
VCAM1	VCAM-1 (1VSC)	−8.1
VEGFA	VEGFA (3QTK)	−8.1