Ethnopharmacological-Based Validation of Polyalthia suberosa Leaf Extract in Neurological, Hyperalgesic, and Hyperactive Gut Disorders Using Animal Models
Table 7
Effect of Polyalthia suberosa in the castor oil-induced diarrheal test.
Group
Dose
Total number of feces (mean ± SEM)
% inhibition of defecation
Total number of diarrhoeal feces (mean ± SEM)
% inhibition of diarrhea
Control
10 ml kg−1
9.67 ± 0.88
00
6.67 ± 0.67
00
Standard (loperamide)
3 mg kg−1
2.33 ± 0.33
76
1 ± 0.0
85.01
PS-250 mg
250 mg kg−1
5.33 ± 0.88
44.89
3.33 ± 0.89
50.07
PS-500 mg
500 mg kg−1
4 ± 0.58
58.64
2 ± 0.58
70.06
indicates < 0.05, indicates < 0.01, and indicates < 0.001 when compared with control.
