Evidence-Based Complementary and Alternative Medicine / 2022 / Article / Tab 2 / Research Article
Evaluation of Wound Healing Activity (Excision Wound Model) of Ointment Prepared from Infusion Extract of Polyherbal Tea Bag Formulation in Diabetes-Induced Rats Table 2 The comparative wound healing efficiency (wound area and % wound closure) of ointment formulation (F1 and F2) and pure drug in diabetic and nondiabetic wound of albino rats.
Days Wound parameters Control group F1 (5%) Chloramphenicol sodium F2 (10%) DW Non-DW DW Non-DW DW Non-DW DW Non-DW 0 Wound area 317.21 ± 0.00 317.21 ± 0.00 317.21 ± 0.00 317.21 ± 0.00 317.21 ± 0.00 317.21 ± 0.00 317.21 ± 0.00 317.21 ± 0.00 % wound closure 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 3rd Wound area 276.91 ± 17.71 267.11 ± 12.71 267.22 ± 12.70 267.23 ± 13.69 276.91 ± 12.17 267.27 ± 19.74 267.12 ± 12.18 267.23 ± 11.27 % wound closure 15.81 ± 6.31 18.71 ± 7.32 18.89 ± 6.13 18.82 ± 4.31 15.53 ± 3.33 18.29 ± 7.23 16.71 ± 3.73 18.90 ± 7.23 6th Wound area 248.30 ± 18.82 239.21 ± 14.82 221.41 ± 12.98 221.34 ± 12.79 212.27 ± 18.19 212.67 ± 11.59 221.41 ± 12.19 187.89 ± 17.09 % wound closure 24.49 ± 7.06 27.81 ± 4.08 33.45 ± 5.72 33.52 ± 1.72 36.21 ± 6.71 36.21 ± 3.66 33.55 ± 6.37 44.19 ± 3.41 9th Wound area 212.67 ± 18.29 164.52 ± 14.11 172.21 ± 11.19 172.21 ± 11.10 164.23 ± 17.11 122.61 ± 10.53 172.31 ± 09.14 122.66 ± 14.44 % wound closure 36.21 ± 8.71 51.52 ± 7.23 49.12 ± 6.21 49.13 ± 5.18 51.52 ± 7.12 64.89 ± 2.52 49.11 ± 7.31 64.82 ± 7.62 12th Wound area 164.52 ± 13.15 122.62 ± 13.31 122.62 ± 10.53 122.56 ± 12.31 122.60 ± 10.43 87.09 ± 8.55 98.51 ± 12.32 57.72 ± 8.81 % wound closure 51.58 ± 5.19 64.91 ± 5.63 64.91 ± 4.61 64.89 ± 4.61 64.89 ± 7.76 76.22 ± 5.13 72.51 ± 8.51 85.55 ± 3.54 15th Wound area 119.09 ± 11.34 68.62 ± 8.62 84.07 ± 9.53 84.07 ± 9.53 54.73 ± 7.71 59.19 ± 7.71 54.73 ± 7.71 31.69 ± 5.89 % wound closure 64.19 ± 5.06 81.71 ± 3.47 76.52 ± 2.30 76.52 ± 6.31 85.51 ± 4.14 84.2 ± 4.53 85.51 ± 4.64 92.97 ± 3.78 18th Wound area 87.72 ± 8.51 45.41 ± 4.81 58.21 ± 12.59 45.42 ± 8.81 34.79 ± 7.89 28.41 ± 6.89 5.67 ± 8.86 3.87 ± 3.64 % wound closure 76.21 ± 4.33 89.51 ± 5.76 85.42 ± 6.62 89.51 ± 4.17 92.91 ± 3.82 94.97 ± 3.51 96.21 ± 0.43 96.51 ± 1.14 21th Wound area 62.18 ± 8.61 34.39 ± 3.18 28.42 ± 5.91 16.10 ± 4.31 5.91 ± 6.12 3.51 ± 1.33 1.92 ± 2.11 2.15 ± 1.23 % wound closure 83.11 ± 3.41 88.91 ± 1.82 93.91 ± 1.65 96.81 ± 2.04 99.81 ± 3.16 99.15 ± 1.41 99.12 ± 5.21 98.13 ± 1.14 Endpoint of complete epithelization 29.31 ± 0.37 33.32 ± 1.43 28.61 ± 2.41 25.12 ± 1.81 26.61 ± 2.54 23 ± 2.81 20.13 ± 3.41 18.61 ± 4.44