Preparation and Safety Evaluation of <i>Centella asiatica</i> Total Glycosides Nitric Oxide Gel and Its Therapeutic Effect on Diabetic Cutaneous Ulcers

<table class="table-group" id="tab29"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td class="align_left">Organ</td><td class="align_center">Control group</td><td class="align_center">Gel group</td><td class="align_center">Positive group</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td class="align_left">Ovary</td><td class="align_center">0.0252 ± 0.0025</td><td class="align_center">0.0272 ± 0.0032</td><td class="align_center">0.0261 ± 0.0047</td></tr><tr><td class="align_left">Uterus</td><td class="align_center">0.2209 ± 0.0037</td><td class="align_center">0.22456 ± 0.0155</td><td class="align_center">0.2187 ± 0.0222</td></tr><tr><td class="align_left">Epididymis</td><td class="align_center">0.4896 ± 0.1134</td><td class="align_center">0.5420 ± 0.0668</td><td class="align_center">0.4673 ± 0.0535</td></tr><tr><td class="align_left">Testis</td><td class="align_center">0.1510 ± 0.0341</td><td class="align_center">0.1493 ± 0.0446</td><td class="align_center">0.17094 ± 0.1063</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Viscera index of <i>Cavia porcellus</i> (%, <span class="nowrap"><svg height="12.248pt" id="M21" style="vertical-align:-0.3499002pt" version="1.1" viewbox="-0.0498162 -11.8981 28.4458 12.248" width="28.4458pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><rect height="0.65243" width="9.9823" x="0" y="-11.1958"></rect><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M748 650H522L515 622L546 617C580 611 587 604 565 575C518 513 469 451 419 393C376 474 349 534 330 580C318 609 325 612 361 618L383 622L392 650H151L144 622C214 616 224 612 257 543L360 327C270 218 187 124 159 95C106 40 92 34 26 28L17 0H252L259 28L236 31C189 37 188 47 209 78C249 136 308 210 377 294L478 79C494 44 487 37 449 32L418 28L409 0H673L680 28C596 34 591 39 554 116L436 361C526 469 574 521 604 553C659 612 669 614 739 622L748 650Z"></path></g><g transform="matrix(.013,0,0,-0.013,12.888,0)"><path d="M535 290V340H323V533H265V340H52V290H265V84H323V290H535ZM535 -22V28H52V-22H535Z"></path></g><g transform="matrix(.013,0,0,-0.013,23.424,0)"><path d="M352 391C352 416 319 448 267 448C236 448 173 423 147 400C107 364 96 332 96 304C96 248 143 210 193 181C241 153 258 124 258 100C258 72 232 38 184 38C151 38 107 66 81 108C77 114 64 116 55 111C34 99 23 84 23 65C23 29 81 -12 134 -12C220 -12 325 61 325 141C325 184 297 215 234 256C194 282 161 309 161 346C161 380 188 401 217 401C255 401 279 380 301 353C308 344 313 341 325 347C341 355 352 371 352 391Z"></path></g></svg>,</span> <i>n</i> = 10).</div>

Evidence-Based Complementary and Alternative Medicine

tab29

Table 29

Table 29: Preparation and Safety Evaluation of <i>Centella asiatica</i> Total Glycosides Nitric Oxide Gel and Its Therapeutic Effect on Diabetic Cutaneous Ulcers 

Table 29 | Preparation and Safety Evaluation of Centella asiatica Total Glycosides Nitric Oxide Gel and Its Therapeutic Effect on Diabetic Cutaneous Ulcers 