Research Article

Preparation and Safety Evaluation of Centella asiatica Total Glycosides Nitric Oxide Gel and Its Therapeutic Effect on Diabetic Cutaneous Ulcers

Table 31

Wound healing rate of diabetic rats.

GroupWound healing rate (%)
3 d7 d10 d14 d

Model27.12 ± 7.3770.01 ± 4.8177.92 ± 5.6991.98 ± 2.85
Blank matrix26.39 ± 9.2468.66 ± 10.8182.21 ± 6.6192.30 ± 3.69
Low dose25.20 ± 6.7076.27 ± 9.8086.21 ± 3.96ΔΔ94.78 ± 4.86
Medium dose46.86 ± 14.31ΔΔ79.78 ± 8.2493.18 ± 2.98ΔΔ98.70 ± 1.18ΔΔ∗∗
High dose28.75 ± 9.1171.39 ± 14.8081.28 ± 15.5192.39 ± 8.27
Positive control39.74 ± 11.71Δ78.83 ± 14.5693.80 ± 5.5697.81 ± 3.54

Note.; versus the model group. ; versus the blank matrix; ; versus the low-dose group. ; ☆☆ versus the medium-dose group.