Tridax procumbens Ameliorates Streptozotocin-Induced Diabetic Neuropathy in Rats via Modulating Angiogenic, Inflammatory, and Oxidative Pathways

Table 7

Impact of TP on Cold hyperalgesia: acetone drop test in Wistar albino rats.

	0 Week	1 Week	2 Week	3 Week	4 Week
Normal control	4.4 ± 0.22	4.43 ± 0.05	4.63 ± 1.21	4.61 ± 1.72	4.53 ± 0.62
Disease control	4.18 ± 0.83	5.95 ± 1.02	6.86 ± 1.27	7.85 ± 1.62	9.75 ± 1.22^##
Standard (Gabapentin)	4.63 ± 1.02	5.43 ± 1.1	5.13 ± 1.32	4.83 ± 1.17	4.4 ± 1.15
TP 250 mg/kg	4.33 ± 0.85	5.93 ± 1.04^a	5.6 ± 1.05^,a	5.18 ± 0.98^,a	5.12 ± 0.57^##,^,aa
TP 375 mg/kg	4.53 ± 0.71	5.89 ± 1.08^a	5.69 ± 0.98^,aa	5.23 ± 1.11^,a	4.73 ± 1.09^##,^,a
TP 500 mg/kg	4.73 ± 1.06	5.58 ± 0.99^,a	5.34 ± 1.03^,a	5.08 ± 1.01	4.67 ± 0.18
TP 500 mg + Gabapentin	4.69 ± 0.86	5.47 ± 1.02^,bb	5.14 ± 1.01^,bb	5.03 ± 0.87^,b	4.45 ± 0.77^,bb