Tridax procumbens Ameliorates Streptozotocin-Induced Diabetic Neuropathy in Rats via Modulating Angiogenic, Inflammatory, and Oxidative Pathways

Table 9

Impact of TP on Grip strength: Rota rod test to assess muscle grip strength to evaluate DPN in Wistar rats.

	0 Week	1 Week	2 Week	3 Week	4 Week
Normal control	133.21 ± 2.32	137.32 ± 2.62	133.85 ± 3.32	139.73 ± 3.92	138.25 ± 3.42
Disease control	133.51 ± 2.41	79.88 ± 4.71^#	63.55 ± 2.14^##	46.45 ± 2.94^##	36.58 ± 2.41^##
Standard (Gabapentin)	135.85 ± 3.12	85.35 ± 1.14	94.1 ± 2.39	109.95 ± 3.23	123.38 ± 2.63
TP 250 mg/kg	138.85 ± 2.65	86.75 ± 2.65^a	80.65 ± 2.23^,a	85.25 ± 3.3^,a	96.93 ± 2.62^##,^,aa
TP 375 mg/kg	138.73 ± 1.39	84.8 ± 2.61^,a	90.72 ± 3.11^,aa	90.15 ± 2.8^,a	106.88 ± 3.03^##,^,a
TP 500 mg/kg	136.75 ± 2.71	91.55 ± 3.52	96.32 ± 3.91^,a	99.09 ± 2.78	116.75 ± 3.26
TP 500 mg + Gabapentin	137.81 ± 2.91	85.45 ± 3.29^,bb	93.15 ± 4.32^,bb	108.01 ± 4.18^,b	124.65 ± 3.72^,bb