[Retracted] Noncoding RNAs and Virus and Treatment in Allergic Rhinitis

Table 1

Summary of regulation and function with miRNA in allergic rhinitis.

miRNA	Expression	Targets	Pathways	Function
miR-133b	Down-regulated	TNF-α, il-4, and INF-α	Nlrp3	Up-regulation of miR-133b significantly reduced OVA-specific IgE concentrations, nasal friction, sneezing frequency, cytokines (TNF-α, IL-4, IL-5, and IFN-γ), and Nlrp3 expression levels [32].
miR-181a	Up-regulated	IL-10 and TGF-β	PI3K/Akt	Up-regulation of miR-181a promotes expression of TGF-β and IL-10 and is involved in the regulation of regulatory T cell differentiation and function in children with allergic rhinitis [33].
miR-375	Up-regulated	Thymic stromal lymphopoietin (TSLP) and type II innate lymphoid cells (ILC2)	JAK2/STAT3	Mediated regulation of ILC2 cells through TSLP in allergic rhinitis [34].
miR-233	Up-regulated	IL-35		Mir-223 and IL-35 levels were associated with Th1/Th2 cytokines, eosinophil counts, and clinical severity [35].
miR-30a-5p	Up-regulated	SOCS3	SOCS1/SOCS3	Involved in T helper cell differentiation [36].
miR-202-5p	Up-regulated	CD4+T	MANT2	Promoted tregs differentiation [28].
miR-29	Down-regulated	CD276		Decreasing inflammatory response [37].