Effects of Descurainia sophia on Oxidative Stress Markers and Thirst Alleviation in Hemodialysis Patients: A Randomized Double-Blinded Placebo-Controlled Cross-Over Clinical Trial
Table 2
Effects of DS on oxidative stress markers and thirst alleviation using the coefficient estimation in linear mixed effect carry-over with random intercept and interaction.
Effect
Estimate
SE
DF
T value
value
Thirst score
Intercept
2.21
0.06
51
34.95
<0.001
D.S. treatment
−0.38
0.11
1452
−3.30
0.001
Time
0.001
0.04
1452
0.03
0.970
Treatmenttime
0.12
0.08
1452
1.59
0.110
Potassium (mEq/L)
Intercept
4.39
0.39
96
11.33
<0.001
D.S. treatment
>0.01
0.07
0.95
0.03
0.979
Time
−0.03
0.07
95
−0.35
0.727
Carry-over
0.23
0.11
96
2.07
0.041
Baseline
0.128
0.05
95
2.51
0.014
Cholesterol (mg/dl)
Intercept
83.14
16.67
98
4.99
<0.001
D.S. treatment
−9.19
4.55
95
2.02
0.046
Time
14.51
4.59
95
3.16
0.002
Carry-over
0.362
6.54
98
0.06
0.956
Baseline
0.041
0.057
95
0.76
0.467
Calcium (mg/dl)
Intercept
3.15
0.89
96
3.53
0.001
D.S. treatment
−0.20
0.29
58
0.70
0.490
Time
0.39
0.29
58
1.38
0.172
Carry-over
−0.10
0.30
96
−0.35
0.731
Baseline
0.56
0.08
58
7.36
<0.001
Triglycerides (mg/dl)
Intercept
111.18
23.77
98
4.68
<0.001
D.S. treatment
−23.93
7.82
97
3.06
0.003
Time
−15.82
7.81
97
−2.02
0.056
Carry-over
−6.39
10.37
98
−0.62
0.539
Baseline
0.055
0.036
97
1.53
0.129
Sodium (mEq/L)
Intercept
119.88
7.94
96
15.10
<0.001
D.S. treatment
0.11
1.02
69
0.11
0.913
Time
0.29
1.04
69
0.28
0.779
Carry-over
3.48
1.12
96
3.12
0.002
Baseline
0.075
0.05
69
1.39
0.168
Malondialdehyde (μmol/L)
Intercept
608.21
231.21
98
2.63
0.010
D.S. treatment
−316.99
81.16
93
3.91
<0.001
Time
−73.68
82.95
93
−0.089
0.377
Carry-over
−137.95
96.43
98
−1.43
0.156
Baseline
0.19
0.06
93
3.22
0.002
TAC (mmol trolox equiv./L)
Intercept
2.46
0.18
98
13.83
<0.001
D.S. treatment
0.98
0.08
95
−12.91
<0.001
Time
0.03
0.08
95
0.43
0.667
Carry-over
−0.12
0.07
98
−1.72
0.089
Baseline
0.25
0.05
95
4.61
<0.001
DS, Descurainia sophia; SE, standard error; DF, degrees of freedom; TAC, total antioxidant capacity.
