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Included study | Country | Age | Included study design | No. of study | No. of patient | Intervention | Comparator | Outcomes | Assessment of methodological quality | Meta-analysis conducted? | Subgroup | Sensitivity | Safety |
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Li [24] (2009) | China | Age ≥ 12 years old | RCT | 12 | 984 | Acupuncture therapy or combined with conventional medicine | Conventional medicine | (2) (3) (6) | Classified by the Cochrane handbook. The version is not stated and the Jadad scale evaluation | Yes | Yes | No | Yes |
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Yan [19] (2015) | China | Any age | RCT | 8 | 755 | Any acupoint stimulation or combined with other therapy | No treatment/placebo or western medication; same other therapy | (1) (8) | Classified by the Cochrane handbook. The version is not stated | Yes | Yes | No | Yes |
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Yao [22] (2016) | China | Any age | RCT | 6 | 406 | Acupuncture or combined with another active therapy | No treatment/placebo/sham acupuncture/other same active therapies | (1) (2) (3) (9) | Classified by the Cochrane handbook. The version is not stated | Yes | No | No | Yes |
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Liang [41] (2016) | China | Any age | RCT | 15 | 1554 | Autohemotherapy or combined with an antihistamine or other treatment | Antihistamine or acupuncture | (1) (2) (3) (7) | Classified by the Cochrane handbook. The version is not stated | Yes | Yes | No | Yes |
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Chen [33] (2016) | China | Any age | RCT | 5 | 545 | Autohemotherapy | Other therapies except for Autohemotherapy | (4) | Classified by the Cochrane handbook. The version is not stated | Yes | No | No | No |
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An [38] (2016) | China | Any age | RCT | 12 | 988 | Autohemotherapy | Other therapies except for autohemotherapy | (1) (3) | Jadad scale evaluation | Yes | Yes | Yes | No |
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Luo [39] (2016) | China | Any age | RCT | 8 | 937 | Autohemotherapy or combined with other therapies | Other therapies | (1) (3) (4) | Cochrane 5.0.1 and Jadad scale evaluation | Yes | Yes | Yes | Yes |
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Liu [35] (2017) | China | Any age | RCT/CCT | 6 | 515 | Autohemotherapy | Conventional western therapy | (4) | Jadad scale evaluation | Yes | No | No | No |
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Pu [28] (2017) | China | Any age | RCT | 10 | 686 | Autohemotherapy or combined with antihistamines | Antihistamine or acupuncture therapy | (2) (3) (4) | Cochrane 5.0.1 | Yes | No | No | Yes |
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Zhang [31] (2018) | China | Any age | RCT | 9 | 751 | Acupoint embedding or combined with other therapies | Other therapies except for acupoint embedding | (1) (5) (6) | Classified by the Cochrane handbook. The version is not stated | Yes | No | Yes | Yes |
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Liang [32] (2018) | China | Any age | RCT/quasi-RCT/CCT | 7 | 528 | Acupoint embedding or combined with other therapies | Other therapies except for acupoint embedding | (4) (6) | Jadad scale evaluation | Yes | No | Yes | No |
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Zhu [21] (2018) | China | Any age | RCT | 7 | 624 | Auriculotherapy or combined with other therapies | Western medicine | (2) (4) (10) | Cochrane 5.0.1 | Yes | No | Yes | Yes |
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Li [37] (2018) | China | Any age | RCT | 14 | 1051 | Autohemotherapy or combined with other therapies | Other therapies except for autohemotherapy | (1) (3) (6) | Classified by the Cochrane handbook. The version is not stated | Yes | No | Yes | Yes |
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Wei [26] (2019) | China | Any age | RCT | 12 | 836 | Acupoint embedding | Other therapies except for acupoint embedding | (2) (3) (4) (6) | Classified by the Cochrane handbook. The version is not stated | Yes | No | Yes | Yes |
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Zhao [40] (2019) | China | Age ≥ 18 years old | RCT | 16 | 1131 | Acupuncture/electroacupuncture (can be moxibustion, cupping, bleeding, etc.) or combined with the same intervention measures as the control group | Western medicine | (1) (3) (6) (7) (10) | Classified by the Cochrane handbook. The version is not stated | Yes | Yes | Yes | Yes |
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Li [36] (2019) | China | Any age | RCT | 11 | 763 | Autohemotherapy combined with other therapies | Other therapies except for autohemotherapy | (3) (6) | Classified by the Cochrane handbook. The version is not stated | Yes | No | No | Yes |
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Wu [29] (2019) | China | Any age | RCT | 13 | 1608 | Autohemotherapy combined with H1 receptor antagonists | H1 receptor antagonists | (1) (2) (3) | Cochrane 5.0.1 | Yes | Yes | Yes | Yes |
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Zhao [30] (2019) | China | Any age | RCT/CCT | 12 | 944 | Autohemotherapy combined with acupuncture and other therapies | Other therapies except for autohemotherapy | (1) (2) (3) (4) | Cochrane 5.1.0 and Jadad scale evaluation | Yes | Yes | Yes | Yes |
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Yao [20] (2019) | China | Any age | RCT | 7 | 512 | Bloodletting therapy or combined with other active therapies | No treatment/placebo/sham bloodletting therapy/other same active therapies | (1) (2) (11) | Classified by the Cochrane handbook. The version is not stated | Yes | No | Yes | Yes |
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Zhao [27] (2020) | China | Age ≥ 18 years old | RCT | 16 | 1131 | Acupuncture or combined with western medicine | Western medicine | (1) (3) (10) | Classified by the Cochrane handbook. The version is not stated | Yes | No | Yes | No |
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Zhang [34] (2020) | China | Any age | RCT/quasi-RCT | 16 | 1325 | Acupuncture | Western medicine | (1) (3) (6) | Jadad scale evaluation | Yes | No | No | No |
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Xiao [23] (2020) | China | Any age | RCT | 12 | 842 | Dry/wet cupping or combination with other therapies | Other therapies | (1) (2) (3) (8) | Cochrane 5.0.1 | Yes | Yes | No | Yes |
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Ke [25] (2021) | China | Any age | RCT | 7 | 510 | Acupuncture therapy combined with herbal decoction | Antihistamine | (1) (3) (4) | Classified by the Cochrane handbook. The version is not stated | Yes | No | Yes | Yes |
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