Research Article
[Retracted] LncRNA-PAX8-AS1 Silencing Decreases Cell Viability, Enhances Apoptosis, and Suppresses Doxorubicin Resistance in Myeloid Leukemia via the miR-378g/ERBB2 Axis
Figure 3
PAX8-AS1 regulated apoptosis-related marker expressions in AML cells and ADM-resistant AML cells. (a) and (b) The protein expressions of Bcl-2, Bax, and C Caspase-3 in HL60 cells transfected with PAX8-AS1 overexpression plasmid were analyzed by Western blot, with GAPDH serving as a reference gene. (c) and (D) The protein expressions of Bcl-2, Bax, and C Caspase-3 in HL60/ADM cells transfected with si-PAX8-AS1 were quantitated by Western blot, with GAPDH serving as a reference gene. ; or ; vs. NC; ∧ vs. siNC (AML: acute myeloid leukemia; ADM: doxorubicin; NC: negative control; PAX8-AS1: PAX8 antisense RNA 1; siNC: siRNA-negative control; si-PAX8-AS1: siRNA-PAX8-AS1).
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