[Retracted] Circ-GTF2I/miR-590-5p Axis Aggravates Myocardial Ischemia-Reperfusion Injury by Regulating Kelch Repeat and BTB Domain-Containing Protein 7

Figure 7

The knockdown of KBTBD7 reverses the proapoptotic effect of circ-GTF2I on neonatal rat cardiomyocytes. (a) KBTBD7 expression level was detected in the neonatal rat cardiomyocyte hypoxia/reoxygenation treatment model. (b) Detection of cell proliferation in the neonatal rat cardiomyocyte hypoxia/reoxygenation treatment model. (c) Cell apoptosis of neonatal rat cardiomyocytes was detected by flow cytometry. (d) Bax expression level was detected in the neonatal rat cardiomyocyte hypoxia/reoxygenation treatment model. (e) Cyt-c expression level was detected in the neonatal rat cardiomyocyte hypoxia/reoxygenation treatment model. (f) Bcl-2 expression level was detected in the neonatal rat cardiomyocyte hypoxia/reoxygenation treatment model. (g) The schema of the relationship of circ-GTF2I, miR-590-5p, and KBTBD7 in MI. Each experiment was repeated three times. All data were expressed as mean ± standard deviation, , , and vs. control.

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