Research Article

Mechanisms Underlying the Differences in the Pharmacokinetics of Six Active Constituents of Huangqi Liuyi Decoction between Normal and Diabetic Nephropathy Mouse Models

Table 1

Content of each component extracted from three batches of Astragalus and Glycyrrhizae (x ± SD, n = 3).

Extraction fractionConstituentsContent (%)Assay methods

Astragalus saponins extractAstragalus saponins72.97 ± 1.06Ultraviolet-visible spectrophotometer (UV)
Astragaloside IV2.72 ± 0.10High performance liquid chromatography (HPLC)
Astragalus flavones extractAstragalus flavones70.58 ± 2.16UV
Calycosin-7-O-β-D-glucoside1.67 ± 0.08HPLC
Calycosin-glucuronide1.45 ± 0.10HPLC
Ononin0.91 ± 0.09HPLC
Formononetin0.32 ± 0.02HPLC
Astragalus polysaccharides extractAstragalus polysaccharides67.12 ± 2.60UV
Glycyrrhizic acid extractGlycyrrhizic acid81.02 ± 1.04HPLC