In Vitro Cercaricidal and Schistosomicidal Activities of the Raffia Wine and Hydroethanolic Extracts of Pedilanthus tithymaloides Linn (Poit). Stem Barks

Table 1

Effective and lethal concentrations of the raffia wine extract and the hydroethanolic extract of Pedilanthus tithymaloides stem bark against Schistosoma mansoni cercariae.

	Time (min)	RwPt	HePt
LC50 (μg/mL)	30	—	—
	60	—	73.91 ± 3.31 CI (51.84–82.70)
	90	—	34.07 ± 3.91 CI (18.15–45.46)
	120	—	28.84 ± 3.30 CI (18.15–43.41)
	150	665.14 ± 42.41 CI (454.36–778.57)	19.26 ± 1.22 CI (13.70–25.73)
	180	617.86 ± 34.65 CI (456.33–732.30)	19.26 ± 1.22 CI (13.70–25.73)
MEC (μg/mL)		250	31.25
MLC (μg/mL)		1000	62.50

RwPt: Raffia wine extract of Pedilanthus tithymaloides stem bark. HePt: hydroethanolic extract of Pedilanthus tithymaloides stem bark. LC₅₀: median lethal concentration. MLC: minimum lethal concentration. MEC: minimum effective concentration. CI: confidence interval.