Inhibitory Effects of Rabdosia rubescens in Esophageal Squamous Cell Carcinoma: Network Pharmacology and Experimental Validation

Figure 2

WGCNA analysis for ESCC genes. (a) Scale-free soft threshold distribution diagram. The horizontal axis represents the power value of the weight parameter, the vertical axis in the left figure represents the square of the correlation coefficient between log(k) and log(p(k)) in the corresponding network, and the vertical axis in the right figure represents the mean value of all gene adjacency functions in the corresponding gene module. (b) Clustering dendrogram. (c) Heat map of correlation between modules and clinical traits. The ordinate is different module, and the abscissa is different trait. Each square represents the correlation coefficient and significance value of a certain module and a certain trait. (d) Network topological overlap measure heatmap plot. The upper part of the figure is the selected gene cluster tree, the lower part is the heat map, and the horizontal and vertical colors represent different modules. (e) Green module MM and GS scatter diagrams. (f) Turquoise module MM and GS scatter diagrams.

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