Research Article

Oligochaeta ramosa (Roxb.) Extract Regulates Lipid Metabolism and Exerts Hepatoprotective Effects in Cadmium-Induced Hepatic Injury in Rats

Table 2

The effect of Cdcl2 on the Body and the Liver Weight. Cdcl2 was administered via the intraperitoneal route on the 1st day of the study followed by AME.Or doses at 200 mg/kg and 400 mg/kg. Each group data is presented as  ± SEM of n = 6 rats. When comparing the cadmium-intoxicated group to the control group, the results are deemed insignificant (ns) if , significant () if , more significant () if , very significant () if , and highly significant () if . When the control group is compared with the intoxicated group, the significance of the results is denoted with (#).

Treatment GroupWeight of animals (g)Liver weight (g)
1st day11th day21st day

Control group193.7 ± 3.65205.2 ± 2.21211.7 ± 2.745.230 ± 0.254
Intoxicated (cdcl2 6.5 mg/kg)235 ± 2.37206.7 ± 2.56147.3 ± 5.376.1954 ± 0.218##
Silymarin, 100 mg/kg215 ± 3.71201 ± 2.35195.7 ± 2.265.407 ± 0.111
AME.Or, 200 mg/kg221 ± 2.62196.8 ± 3.40168.8 ± 2.126.104 ± 0.379ns
AME.Or, 400 mg/kg219 ± 3.3202.3 ± 2.82186 ± 2.125.905 ± 0.361

± indicates a margin of error.