Oligochaeta ramosa (Roxb.) Extract Regulates Lipid Metabolism and Exerts Hepatoprotective Effects in Cadmium-Induced Hepatic Injury in Rats

Table 3

The Effect of AME.Or on Lipid Profile. Cdcl₂ was administered via the intraperitoneal route on the 1^st day of study followed by AME.Or doses at 200 mg/kg and 400 mg/kg. The results are presented as mean ± SEM (n = 6); each group is analyzed using one-way ANOVA followed by Bonferroni’s test. When the intoxicated group is compared to treatment groups, results are considered nonsignificant (ns) if , significant () if , more significant () if , very significant () if , and highly significant () if . When the control group is compared with the intoxicated group, the significance of the results is denoted with (^#).

Lipid profile	Groups	A (normal control)	B (cdcl26.5 mg/kg)	C (silymarin 100 mg/kg)	D (AME.Or 200 mg/kg)	E (AME.Or 400 mg/kg)
	Days
Total cholesterol (mg/dl)	11^th day	137.800 ± 3.584	241.67 ± 4.12^###	174.167 ± 5.677	206.667 ± 5.149	181.167 ± 2.548
	21^st day	138.462 ± 5.284	233.50 ± 4.023^###	144.167 ± 6.867	174.000 ± 4.258	150.500 ± 5.290
Triglycerides (mg/dl)	11^th day	65.667 ± 6.103	125.167 ± 4.012^###	90.067 ± 3.562	106.167 ± 5.056^ns	99.167 ± 3.961
	21^st day	65.500 ± 5.506	120.500 ± 4.478^###	65.833 ± 6.041	90.550 ± 4.695	74.000 ± 6.836
HDL (mg/dl)	11^th day	54.833 ± 3.978	28.000 ± 3.141^###	44.167 ± 6.887	36.500 ± 2.187	42.833 ± 5.212
	21^st day	54.500 ± 2.997	29.167 ± 2.971^###	55.833 ± 3.870	46.167 ± 3.683	53.333 ± 2.459
LDL (mg/dl)	11^th day	69.833 ± 4.164	188.633 ± 6.972^###	111.987 ± 9.575	148.933 ± 5.401	118.890 ± 3.913
	21^st day	70.862 ± 3.800	173.067 ± 3.932^###	75.167 ± 7.698	105.000 ± 6.272	82.367 ± 3.194
VLDL (mg/dl)	11^th day	13.133 ± 1.221	25.033 ± 0.802^###	18.013 ± 0.712	21.233 ± 1.011	21.233 ± 1.011
	21^st day	13.100 ± 1.101	24.100 ± 0.896^###	13.167 ± 1.208	17.133 ± 1.010	14.800 ± 1.367
Atherogenic index	11^th day	1.325 ± 0.154	7.288 ± 1.012^###	3.068 ± 0.734	4.195 ± 0.413	2.833 ± 0.213
	21^st day	1.332 ± 0.119	6.340 ± 0.810^###	1.375 ± 0.183	2.375 ± 0.277	1.553 ± 0.064

± indicates a margin of error.