Research Article

Etlingera elatior Flower Aqueous Extract Protects against Oxidative Stress-Induced Nephropathy in a Rat Model of Type 2 Diabetes

Table 3

Levels of oxidative stress parameters in experimental groups.

ParametersControlT2DRMetEEAE

MDA (ng/mL)187.31 (13.94)a385.72 (27.27)185.61 (34.30)b217.48 (26.72)a
SOD (U/mL)44.82 (1.81)c32.33 (2.46)42.39 (0.72)b43.04 (1.01)c
CAT (U/mL)195.65 (27.87)a101.54 (11.42)185.84 (11.57)a181.26 (18.65)a
GSH (μmol/L)87.26 (15.21)a53.43 (10.47)87.48 (9.63)a90.89 (18.96)b
T-AOC (mmol/L)3.86 (0.09)c3.65 (0.05)3.81 (0.07)a3.83 (0.06)b

Data represent the mean (standard deviation), n = 8 per group. , , and cp < 0.001 compared to T2DR. T2DR: untreated T2DR, Met: 250 mg/kg metformin-treated T2DR, EEAE: 1000 mg/kg EEAE-treated T2DR, MDA: malondialdehyde, SOD: superoxide dismutase, CAT: catalase, GSH: glutathione, T-AOC: total antioxidant capacity. Statistical analysis was performed using the one-way ANOVA followed by Tukey’s post hoc test.