Cryptotanshinone Suppressed Postmenopausal Osteoporosis by Preventing RANKL-Mediated Osteoclastogenesis against Kidney Injury

Figure 5

Role of osteoclast differentiation pathway in the process of CPT treatment-attenuated osteoclast differentiation. RAW 264.7 cells were pretreated with CPT (1, 10 μM) for 1 h in response to RANKL (50 ng/mL) for 5 days, and the expression of NFATc1, c-Fos, and cathepsin K was detected by Western blotting.