Antitumor Potential of Sericite Treatment Mediated by Cell Cycle Arrest in Triple-Negative MDA-MB231 Breast Cancer Cells

Figure 2

Sericite regulated HSPs and ROS in MDA-MB231 cells. MDA-MB231 cells were treated with different concentrations of sericite for 24h. (a–d) mRNA expressions were detected using an Amplex Red assay. (f) Phosphorylation of p66shc was measured by immunoblotting. (g, h) mRNA expressions of p22phox and NOX4 were detected by qPCR. GAPDH was used as an internal control for both immunoblotting and qPCR. All data are representative of three independent experiments. Data are presented as mean ± SEM of three independent experiments. P < 0.05 vs. 0 mg/mL sericite-treated MDA-MB231 cells. ^#P < 0.05 vs. 1 mg/mL sericite-treated MDA-MB231 cells.

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