Antitumor Potential of Sericite Treatment Mediated by Cell Cycle Arrest in Triple-Negative MDA-MB231 Breast Cancer Cells

Figure 4

Sericite attenuates HSP- and ROS-related pathways in an MDA-MB231 xenograft mouse model. (a–d) mRNA expressions of HSPs in saline-fed mice and 1 mg/kg sericite-fed mice. (e) Intracellular ROS was detected using an Amplex Red assay. (f) Phosphorylation of p66shc was measured by immunoblotting. (g and h) mRNA expressions of p22phox and NOX4 were detected by qPCR. All data are representative of three independent experiments. Data are presented as mean ± SEM of three independent experiments. P < 0.05 vs. sericite-fed mice.

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