Pharmacodynamics and Cellular Uptake of Peimine and Peiminine in Inflammatory Model Non-Small-Cell Lung Cancer Epithelial Cells (A549)

Table 5

Stability investigated for peimine and peiminine under different conditions.

Component	Spiked (ng/mL)	Short-time stability		Long-time stability		Freeze-thaw (three cycles)
		Measured (ng/mL)	Accuracy (%)	Measured (ng/mL)	Accuracy (%)	Measured (ng/mL)	Accuracy (%)
Peimine	2.004	2.06 ± 0.13	2.96	2.07 ± 0.09	3.46	1.99 ± 0.17	−0.69
	20.04	20.55 ± 1.17	2.52	20.39 ± 0.92	1.74	20.62 ± 1.37	2.89
	200.4	200.81 ± 1.31	0.21	200.69 ± 2.84	0.15	200.84 ± 3.22	0.22
Peiminine	1.42	1.46 ± 0.07	2.46	1.44 ± 0.07	1.29	1.43 ± 0.06	0.94
	14.2	14.52 ± 0.57	2.27	14.42 ± 0.79	1.57	14.53 ± 0.49	2.35
	142	144.12 ± 5.57	1.49	143.02 ± 3.70	0.71	141.19 ± 2.97	−0.57