The Effects of Moxibustion on Learning and Memory and m6A RNA Methylation in APP/PS1 Mice

Figure 3

Moxibustion reduces Tau and p-Tau protein expression both in the hippocampal and cortical regions of APP/PS1 mice. Immunofluorescence staining results of hippocampal CA1 (a), CA3 (b), DG (c), and cortical (d) area with FITC 488-conjugated tau and p-tau antibody (green). Protein expression of Tau in hippocampal (e) and cortex (f) tissues. p-Tau protein immunofluorescence results in CA1 (g), CA3 (h), DG (i), and cortical regions (j). White arrows indicate positive expression of Tau and p-Tau. Magnification in (a–d) = 200×. Scale bars in (a–d) represent 50 μm. ^∗P < 0.05.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)

(j)