In Vitro Antibacterial Potential against Multidrug-Resistant Salmonella, Cytotoxicity, and Acute Biochemical Effects in Mice of Annona muricata Leaf Extracts

Table 1

Minimum inhibitory concentrations of Annona muricata leaf extracts against multidrug-resistant Salmonella isolates.

Extracts	MIC values (mg/mL)	No. of isolates	Cumulative no. of isolates	Activity
ANOHex	0.0625	3	3	High
	0.125	2	5
	2	1	6
	4	3	9	Moderate
	6	1	10
	8	6	16	Low
ANOMET	0.0625	4	4	High
	0.25	2	6
	0.5	2	8
	0.125	3	11
	4	1	12	Moderate
	6	2	14
	8	2	16	Low

Interpretation of MIC values (mg/mL): ≤2, high activity; >2 and <6, moderate activity; >6, low activity [26]. Extracts: ANO_Hex and ANO_Met: hexane and methanol extracts of A. muricata, respectively. MICs, minimum inhibitory concentrations.