Effects of Resveratrol Against Induced Metabolic Syndrome in Rats: Role of Oxidative Stress, Inflammation, and Insulin Resistance

Table 2

Effect of resveratrol on the serum liver function indicators in HFFD-induced MS rats.

Parameters	Experimental groups
	Cont.	MS	Res	MS + Res
ALT (U/L)	44.80 ± 2.15^b	59.20 ± 3.02^a	43.60 ± 2.87^b	47.20 ± 3.51^b
AST (U/L)	53.80 ± 2.31^c	76.80 ± 2.21^a	55.50 ± 2.20^c	63.60 ± 2.44^b
ALP (U/L)	333.14 ± 18.73^b	424.74 ± 14.77^a	322.56 ± 13.38^b	345.10 ± 11.03^b
Total bilirubin (mg/dl)	0.22 ± 0.19^b	0.40 ± 0.02^a	0.20 ± 0.03^b	0.37 ± 0.02^a
Direct bilirubin (mg/dl)	0.13 ± 0.03^b	0.28 ± 0.02^a	0.13 ± 0.01^b	0.23 ± 0.01^a
Indirect bilirubin (mg/dl)	0.09 ± 0.02^ab	0.12 ± 0.01^ab	0.07 ± 0.02^b	0.14 ± 0.02^a
Total protein (g/dl)	9.41 ± 0.20^a	7.72 ± 0.06^b	9.24 ± 0.37^a	8.00 ± 0.17^b
Albumin (g/dl)	4.73 ± 0.26^a	4.39 ± 0.10^a	4.66 ± 0.10^a	4.60 ± 0.15^a
Globulin (g/dl)	4.68 ± 0.12^a	3.33 ± 0.12^b	4.58 ± 0.34^a	3.40 ± 0.09^b
A/G ratio	1.02 ± 0.76^b	1.32 ± 0.04^a	1.04 ± 0.09^b	1.35 ± 0.06^a

Values are presented as mean ± SEM for eight rats per group. Means with different superscripts in the same row differed significantly, . Cont.: control; MS: metabolic syndrome; Res: resveratrol; MS + Res: metabolic syndrome + resveratrol; ALT: alanine aminotransferase; AST: aspartate aminotransferase; ALP: alkaline phosphatase; A/G ratio: albumin/globulin ratio.